Surescripts Reports Record Health Data Transactions and Prior Authorization Automation Gains in 2025

  • Surescripts exchanged 30.5 billion health intelligence transactions in 2025, a 12.3% increase from 2024.
  • Real-Time Prescription Benefit usage reached 1 billion responses, helping patients save over $55 million.
  • Prior authorization automation reduced approval times to just 18 seconds for 83 medications across 20 health systems.
  • GLP-1 prescriptions surged nationwide, with Puerto Rico and Vermont among the fastest-growing states.

Surescripts' 2025 report underscores the growing demand for seamless health data interoperability, particularly as prior authorization automation reduces friction in patient care. The company's dominance in health intelligence transactions positions it as a critical infrastructure player in an industry increasingly reliant on real-time data exchange. The surge in GLP-1 prescriptions also highlights emerging trends in chronic disease management and obesity treatment.

Interoperability Expansion
The pace at which Surescripts can scale its network to include more healthcare professionals and insured Americans will determine its long-term dominance in health data exchange.
Regulatory Scrutiny
Whether prior authorization automation gains could attract regulatory attention due to potential impacts on payer-provider dynamics.
GLP-1 Market Trends
How the surge in GLP-1 prescriptions will affect Surescripts' transaction volumes and partnerships with pharmaceutical companies.