SOPHiA GENETICS Boosts Revenue 27% on U.S. and BioPharma Growth

  • SOPHiA GENETICS reported Q2 2026 revenue of $23.3M, up 27% YoY.
  • Adjusted EBITDA loss improved by 27% YoY to $8.8M.
  • Company signed two companion diagnostic programs with AstraZeneca, its first-ever BioPharma deals.
  • U.S. revenue grew 64% YoY, driven by 60% volume growth and new customer wins.
  • Raised full-year 2026 revenue guidance to $94M–$96M (prior: $92M–$94M).

SOPHiA GENETICS's Q2 2026 results highlight its strategic pivot toward BioPharma partnerships and U.S. market expansion, key growth drivers in the AI-driven precision medicine sector. The company's ability to improve adjusted EBITDA loss while raising revenue guidance underscores its operational discipline amid competitive pressures in genomics and diagnostics.

BioPharma Expansion
Whether SOPHiA GENETICS can sustain BioPharma growth momentum into 2027 following its first-ever companion diagnostic deals with AstraZeneca.
U.S. Market Penetration
The pace at which the company can convert its 64% YoY U.S. revenue growth into profitable, scalable operations.
Operational Efficiency
How targeted cost actions and AI-driven productivity improvements will impact adjusted EBITDA breakeven timeline by year-end 2026.