Penumbra Reports Strong Q4 and Full-Year 2025 Growth Despite China Headwinds

  • Q4 2025 revenue of $383.0M–$384.8M, up ~21.4%–22.0% YoY (ex-China: ~23.2%–23.8%)
  • Full-year 2025 revenue of $1.40B–$1.40B+, up ~17.3%–17.5% YoY (ex-China: ~24.7%–24.9%)
  • Q4 gross margin of 67.9%–68.1%; full-year at 67.1%
  • Operating income of $56.9M–$60.4M in Q4 (margin: 14.8%–15.7%); full-year at $186.9M–$190.4M (margin: 13.3%–13.6%)

Penumbra's strong 2025 performance highlights its leadership in thrombectomy solutions, but China's underperformance raises strategic questions about regional diversification. The company's ability to balance innovation with operational efficiency will be critical as it competes in a consolidating medical-device sector.

China Market Recovery
Whether Penumbra can stabilize or reverse China-related revenue declines amid broader regional challenges.
Margin Sustainability
How the company maintains gross margins near 68% while scaling operations globally.
Innovation Pipeline
The pace at which Penumbra advances its CAVT and other clot-removal technologies to sustain growth.