National Comprehensive Cancer Network, Inc. (NCCN)

The National Comprehensive Cancer Network (NCCN) is a not-for-profit alliance of 34 leading cancer centers in the United States, dedicated to patient care, research, and education. Its mission is to define and advance quality, effective, equitable, and accessible cancer care and prevention globally. The organization's headquarters are located in Plymouth Meeting, Pennsylvania.

NCCN's core offerings include the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), which are evidence-based, expert consensus-driven recommendations for cancer management, covering 95-97% of cancers. These guidelines are continuously updated and serve as a recognized standard for clinical direction and policy in cancer care worldwide. The organization also produces NCCN Guidelines for Patients®, a range of compendia (Drugs & Biologics, Biomarkers, Radiation Therapy), Chemotherapy Order Templates, and Imaging Appropriate Use Criteria. Additionally, NCCN provides continuing education, policy and advocacy initiatives, research collaboration, and publishes the Journal of the National Comprehensive Cancer Network (JNCCN).

Recent leadership appointments include Crystal S. Denlinger, MD, as Chief Executive Officer, Renuka Iyer, MD, as Chief Medical Officer (effective February 2026), and Nancy L. Lewis, MD, MBS, FACP, as Chief Scientific Officer (effective May 2026). In May 2026, NCCN launched a new free weekly email service to provide updates on its guidelines. The NCCN Guidelines are widely utilized by healthcare professionals, payers, and patients globally, solidifying NCCN's position as a key authority in oncology standards.