Orange County Urology First in California to Adopt Francis Medical's Vanquish Water Vapor Ablation — Francis Medical, Inc.

Event summary

Orange County Urology Associates (OCUA) performed the first commercial Vanquish® Water Vapor Ablation procedures in California on July 7, 2026.
The Vanquish System, FDA-cleared in late 2025, uses thermal energy from sterile water vapor for targeted prostate tissue ablation.
VAPOR 2 study results showed 91% elimination of targeted MRI-visible intermediate-risk disease in 110 patients with no device-related serious adverse events.
Dr. Daniel Su reported a manageable learning curve and strong clinical support during integration into OCUA's practice.

The big picture

Francis Medical's Vanquish System represents a strategic shift towards minimally invasive, outpatient options for prostate cancer treatment. The adoption by OCUA signals potential for broader uptake in the urology sector, particularly as practices seek effective and practical solutions for intermediate-risk localized prostate cancer. The technology's ability to minimize impact on surrounding nerve bundles could make it a compelling alternative to more invasive procedures.

What we're watching

Adoption Pace: How quickly other urology practices in California and beyond will integrate the Vanquish System into their routines.
Clinical Efficacy: Whether long-term data will confirm the initial positive outcomes from the VAPOR 2 study.
Market Penetration: The pace at which Francis Medical can expand its commercial reach beyond early adopters.