City of Hope

City of Hope is a private, non-profit clinical research center, hospital, and graduate school dedicated to the prevention, treatment, and cure of cancer, diabetes, and other life-threatening diseases. Its mission is to make hope a reality for all touched by these conditions and to deliver advanced cures to patients. Founded in 1913, City of Hope is headquartered in Duarte, California.

The institution operates as a National Cancer Institute (NCI)-designated comprehensive cancer center, offering a broad spectrum of clinical services. These include surgical oncology, medical oncology (featuring bone marrow/stem cell transplant, immunotherapy, and CAR-T Cell programs), radiation oncology, and precision medicine. City of Hope is recognized for its significant contributions to biomedical research, including breakthroughs in recombinant DNA technology, gene therapy, human synthetic insulin, and monoclonal antibodies.

Consistently ranked among the nation's top hospitals for cancer care by U.S. News & World Report, City of Hope is led by Chief Executive Officer Robert Stone. The organization has recently expanded its national footprint with clinical care locations across Southern California and in metropolitan areas such as Atlanta, Chicago, and Phoenix. Notable recent developments include the launch of HopeLLM, a proprietary generative AI platform aimed at enhancing personalized patient care, and the opening of its largest outpatient cancer center.