Cincinnati Children's Launches Multicenter Trial to Boost CHD Family Support
Event summary
- Cincinnati Children's Hospital Medical Center is launching the BOND trial, a multicenter study to improve support for families facing congenital heart disease (CHD).
- The three-year study will recruit 350 families across 17 heart centers and test two interventions: HeartGPS psychological support program and breastfeeding clinical practice guidelines.
- HeartGPS, led by Nadine Kasparian, PhD, PMH-C, aims to reduce parental anxiety and depression starting from prenatal diagnosis.
- The trial uses an adaptive platform structure to test multiple strategies simultaneously, accelerating evidence generation.
The big picture
While survival rates for CHD have improved with better surgical technologies, the BOND trial addresses the critical gap in psychological support and developmental care. This initiative reflects a growing industry focus on holistic pediatric healthcare outcomes, moving beyond acute treatment to long-term family well-being.
What we're watching
- Intervention Efficacy
- Whether HeartGPS and breastfeeding interventions can demonstrably improve parent-infant bonding and infant development outcomes.
- Adaptive Platform Success
- The pace at which the adaptive platform structure accelerates evidence generation compared to traditional trial methods.
- Care Model Adoption
- How study findings will influence clinical guidelines and hospital service offerings beyond the 17 participating centers.
