$100M Series C for Cadence Signals AI's Push into Chronic Care Automation — Cadence

Event summary

$100M Series C led by Spark Capital, with participation from 7 other investors.
Partnerships expanded to include Duke Health and Texas Health Resources, bringing total health system affiliations to over 20.
Treats more than 100,000 active patients, saving Medicare approximately $2.7 million weekly.
Tripled annual recurring revenue in 2025.

The big picture

Cadence's funding and partnerships underscore the growing industry shift toward AI-driven chronic care management, aiming to address the clinical labor shortage and high costs of unmanaged chronic diseases. The company's ability to demonstrate peer-reviewed outcomes and economic proof positions it as a potential model for bending the healthcare cost curve through technology.

What we're watching

Scale and Adoption: Whether Cadence can sustain its rapid growth across new health systems while maintaining clinical outcomes.
AI Integration: The pace at which AI agents advance in sophistication and regulatory acceptance within care delivery workflows.
Value-Based Care: How effectively Cadence can expand its value-based care models to further reduce healthcare costs without compromising quality.