TransMedics Bets Big on Boston with Massive New HQ and Lab Hub

SOMERVILLE, MA – January 12, 2026 – TransMedics Group, Inc., a pioneer in organ transplant technology, has announced a landmark deal that solidifies its future in the Greater Boston area and signals a new phase of aggressive growth. The company has signed a 16-year lease for a new 498,000-square-foot global headquarters and manufacturing hub at Assembly Innovation Park, a premier life sciences campus developed by BioMed Realty. The move consolidates TransMedics' operations into a single, state-of-the-art facility and represents one of the most significant life science real estate transactions in the region in recent years.

Fueling a Revolution in Organ Transplantation

The massive expansion is a direct reflection of TransMedics' explosive financial performance and the growing adoption of its groundbreaking Organ Care System (OCS™). The company, which aims to revolutionize the process of organ transplantation for patients with end-stage heart, lung, and liver failure, has seen its revenue skyrocket. Recent financial reports show staggering year-over-year revenue growth exceeding 150%, a clear indicator of the market's embrace of its technology. This growth has propelled the firm from net losses to profitability, creating the financial foundation for such a monumental investment.

The OCS™ platform is designed to address the critical unmet need for more and better organs. By preserving donor organs in a warm, metabolically active state outside the body, the technology improves organ viability, allows for assessment prior to transplant, and potentially increases the number of usable organs. The new Somerville facility will serve as the nerve center for this mission, combining research and development, advanced manufacturing, and corporate leadership under one roof.

“We selected our new headquarters to support the full scale and complexity of our mission,” said Waleed Hassanein, M.D., President and CEO of TransMedics, in a statement. "Our innovation will accelerate and thrive in this world-class facility that BioMed Realty built. It provides the infrastructure, flexibility, and long-term growth capacity we need to support our teams and the broader transplant community as we continue to advance life-saving transplant technologies and scale our impact globally.”

A Landmark Deal in a Competitive Biotech Hub

This lease is a powerful statement about the enduring strength of the Greater Boston life sciences real estate market. While some market analyses have pointed to rising vacancy rates due to new construction, this full-building commitment underscores a prevailing "flight to quality." Companies with strong growth trajectories are actively seeking large, modern, and highly specialized facilities, making premium properties like Assembly Innovation Park a prized commodity.

The deal validates BioMed Realty's strategy of developing purpose-built infrastructure in the world's top innovation clusters. Backed by Blackstone Real Estate, BioMed has become a dominant force in providing the physical backbone for scientific discovery.

"We are delighted to welcome TransMedics to BioMed Realty’s highly differentiated Assembly Innovation Park campus," commented Bill Kane, President, East Coast and U.K. Markets at BioMed Realty. He emphasized that the developer's hands-on, expert-led approach allows them to create spaces that support the strategic initiatives of tenants like TransMedics.

The location itself is a key asset. Situated in Somerville’s Assembly Square, the campus offers direct access to Interstate 93 and the MBTA Orange Line, connecting TransMedics to Greater Boston's unparalleled ecosystem of academic institutions, world-renowned hospitals, and a deep well of scientific talent. This strategic positioning is crucial for a company looking to attract and retain the best minds in the field.

Building for the Future of Science and Wellness

Beyond its sheer scale, the new 12-story building is a model for the future of scientific workplaces. The facility has achieved both LEED® Platinum and WELL certifications, the highest standards for environmental sustainability and employee well-being, respectively.

LEED Platinum certification, awarded by the U.S. Green Building Council, signifies exceptional performance in energy efficiency, water conservation, and the use of sustainable materials. This translates to lower operational costs, a reduced carbon footprint, and a commitment to environmental stewardship. For a manufacturing-intensive company, this level of efficiency is a significant operational and financial advantage.

Simultaneously, the WELL certification focuses on the human element. Administered by the International WELL Building Institute, it ensures the building is optimized for human health through superior air and water quality, access to natural light, acoustic comfort, and spaces that promote mental and physical fitness. In the hyper-competitive life sciences industry, where the war for talent is fierce, a workplace designed to enhance employee well-being is a powerful recruitment and retention tool.

“The Assembly Innovation Park campus was designed to provide flexibility and operational resilience that companies like TransMedics need to accelerate innovation and change lives,” noted Colleen O’Connor, Executive Vice President, Market Lead, East Coast & UK Markets at BioMed Realty. This dual focus on operational excellence and human-centric design is becoming the new benchmark for mission-critical R&D facilities.

Transforming Assembly Square into an Innovation Powerhouse

TransMedics' arrival marks a pivotal moment for Somerville's Assembly Square. Once known primarily for its retail and entertainment offerings, the district is rapidly evolving into a dynamic mixed-use neighborhood and a bona fide innovation hub. The addition of hundreds of high-value jobs in research, manufacturing, and corporate leadership will provide a substantial boost to the local economy and diversify its commercial base.

This development aligns perfectly with the city of Somerville's long-term vision to attract technology and life science companies, leveraging the area's recent infrastructure upgrades, including the Green Line Extension. The long-term presence of a publicly traded, high-growth medical technology firm anchors the district as a serious player within the broader Boston-Cambridge biotech cluster.

Further signaling its long-term commitment, TransMedics also acquired an adjacent land parcel and a portion of the parking structure. This strategic purchase provides the company with a clear path for future expansion, ensuring that its new home can grow alongside its ambitious mission to transform organ transplantation globally. The investment not only provides a home for TransMedics but also plants a flag for the future of the life sciences industry in Somerville.