Profusa Partners with Mayo Clinic to Expand Oxygen Monitoring Tech Applications

  • Profusa and Mayo Clinic entered a know-how agreement on February 12, 2026, to advance clinical applications of oxygen monitoring technologies.
  • The collaboration aims to accelerate regulatory approval and commercialization of Profusa’s Lumee™ wearable continuous tissue oxygen monitoring product.
  • Target indications include cardiovascular, renal, multi-organ, and orthopedic applications, with a focus on postoperative perfusion monitoring.
  • Mayo Clinic has a financial interest in the technology and will use any revenue to support its not-for-profit mission in patient care, education, and research.

This collaboration marks a strategic move to validate and expand the clinical utility of Profusa’s oxygen monitoring technology. The partnership with Mayo Clinic, a leader in medical research and patient care, could accelerate the adoption of Lumee™ and other products in high-impact clinical areas. The focus on postoperative perfusion monitoring aligns with broader industry trends toward personalized medicine and earlier disease detection.

Regulatory Approval
The pace at which Profusa can secure regulatory approval for Lumee™ in the U.S. will determine the timeline for commercialization.
Market Expansion
Whether Profusa can successfully expand its oxygen monitoring technology into new clinical indications beyond critical limb ischemia.
Execution Risk
How Profusa’s ability to leverage Mayo Clinic’s expertise will impact the development and commercialization of new products.