ISS National Lab Research Drives FDA Approval, Startup Funding

  • The ISS National Lab published a record 76 peer-reviewed studies in fiscal year 2025, up from 51 the previous year.
  • Research from the lab directly informed the FDA approval of a new injectable cancer therapy from Merck & Co.
  • Startup Encapsulate secured additional NASA funding and patents related to tumor-on-a-chip technology developed on the ISS.
  • Orbit Fab signed a contract with the U.S. Space Force for in-orbit refueling services, marking an operational milestone.

The ISS National Lab's record output underscores the growing recognition of microgravity as a unique research environment, particularly valuable for biomedical and materials science applications. This trend is fueled by increasing private sector investment in space-based research and a desire to leverage the ISS as a platform for technology development and commercialization. The success of startups like Encapsulate and Orbit Fab demonstrates the potential for LEO to drive innovation and create new markets.

Commercialization
The continued translation of ISS research into commercially viable products will be crucial for justifying ongoing investment in the lab and demonstrating its return on investment.
Funding
NASA's future funding priorities and the availability of private capital will dictate the pace of innovation and expansion of ISS-based research programs.
Sustainability
The long-term viability of the ISS itself, given planned decommissioning dates, will impact the ability of research programs to continue generating results and commercial opportunities.