IV Drip Gold Rush: Prime IV's New Capital Fuels National Growth

JUPITER, Fla. – December 17, 2025 – In a significant move highlighting the soaring investor confidence in the wellness sector, Prime IV Hydration & Wellness has secured a major senior secured financing package from investment firm Lafayette Square. The deal, orchestrated by boutique investment bank Boxwood Partners, injects substantial capital into one of the nation's fastest-growing franchise systems, positioning it to further dominate the burgeoning intravenous (IV) therapy market.

This strategic partnership provides Prime IV with the financial firepower to accelerate its already aggressive national expansion, bolster its support systems for a growing network of franchisees, and continue innovating its suite of wellness services. The move comes as consumers increasingly pivot from reactive healthcare to proactive, personalized wellness solutions, creating a fertile ground for accessible and science-backed therapies.

The Fuel for a Wellness Empire

The financing from Lafayette Square is earmarked to support several key strategic priorities for the wellness franchise. A primary focus will be on scaling the company’s operational infrastructure to manage its explosive growth, which already includes 189 locations open or in development across 40 states. The capital will also be used to strengthen franchisee support systems, invest in national brand awareness, and accelerate the research and development of new service offerings.

Founded by Amy Neary, Prime IV has rapidly emerged as a category leader by offering a spa-like experience for services ranging from customized IV nutrient drips to vitamin injections and NAD+ treatments. "Our mission has always been simple: make science-backed wellness more accessible," said Amy Neary, Founder and CEO of Prime IV. "With Lafayette Square's support, and Boxwood's steady guidance throughout this process, we can grow in a way that stays true to who we are. This partnership gives us the ability to better support our franchisees while continuing to innovate for the members who trust us every day."

Advising on the deal, Boxwood Partners emphasized the strong foundation built by Neary and her team. "Prime IV has built an impressive platform in one of the most dynamic segments of the wellness industry," noted Patrick Galleher, Managing Partner at Boxwood Partners. "Amy and her team have established a strong foundation with compelling unit economics, a passionate member base, and a highly engaged franchise community. Lafayette Square is the ideal capital partner to help accelerate the next phase of growth."

A Market on the Rise

The timing of the investment could not be more opportune. The global IV hydration therapy market, estimated at nearly $5 billion in 2024, is on a steep upward trajectory. Industry analysts project the market could more than double to over $12.6 billion by 2035, driven by a powerful cultural shift toward preventative health and personalized wellness. Consumers are increasingly seeking out services that offer tangible benefits for energy, immunity, anti-aging, and recovery, and IV therapy clinics are meeting that demand directly.

North America currently stands as the largest market for these services, benefiting from high consumer awareness, disposable income, and an advanced healthcare infrastructure that lends credibility to the sector. Prime IV has capitalized on this trend by establishing a strong presence across the United States, offering a membership-based model that encourages recurring client visits and builds a predictable revenue stream for its franchisees.

The Prime IV Blueprint: Rapid Growth and High Marks

Prime IV's ascent has been nothing short of meteoric. The company’s growth is evidenced by numerous industry accolades, including being ranked #1 in the IV Therapy Category by Entrepreneur Magazine's prestigious Franchise 500 list for both 2024 and 2025. It also secured a spot on the Inc. 5000 list of fastest-growing private companies, a testament to its aggressive expansion and strong system-wide performance.

Central to its appeal is a franchise model that boasts compelling unit economics. Reports indicate that the average gross revenue for a Prime IV location significantly outpaces the sub-sector average, a figure supported by a low-overhead operational model that can be run by a small, highly trained medical staff. This combination of strong potential returns and comprehensive corporate support has made it an attractive opportunity for entrepreneurs looking to enter the wellness space.

A Partnership with Purpose

The choice of Lafayette Square as a capital partner is particularly noteworthy. The investment firm distinguishes itself with a unique philosophy that blends financial returns with social impact. It focuses on providing non-dilutive capital—allowing founders like Amy Neary to retain ownership and control—while lending to middle-market companies in what it terms "working-class places."

A key differentiator for Lafayette Square is its affiliated "Worker Solutions®" platform, which aims to improve job quality and employee well-being for its portfolio companies. This focus on strengthening the workforce from within aligns with Prime IV's need to maintain a premium guest experience through a highly engaged and well-supported staff, even as it scales.

For Boxwood Partners, the transaction further cements its reputation as a leading M&A advisor in the franchise sector. With a long history of guiding founder-led brands through critical growth stages, their involvement provided the strategic expertise necessary to connect Prime IV with a capital partner that matched both its financial needs and its cultural ethos.

Navigating the Risks in a Trendy Sector

Despite the impressive growth and market tailwinds, the path forward is not without its challenges. The wellness industry, and IV therapy in particular, is sometimes viewed as trendy, raising questions about long-term, sustained demand. As noted in the company's 2024 Franchise Disclosure Document (FDD), the risk that the industry could be a "fad business" is a factor for potential franchisees to consider.

Furthermore, the FDD revealed the financial pressures associated with such rapid scaling, noting a negative net worth and net losses in recent years—a common scenario for high-growth companies heavily reinvesting in expansion. These figures underscore the critical importance of the new financing from Lafayette Square. The capital infusion is designed not just to fuel further growth but also to fortify the company's financial foundation, allowing it to mature its operations and enhance franchisee profitability.

With fresh capital and a strategic partner focused on long-term stability, Prime IV is now better equipped than ever to solidify its market leadership. This strategic infusion of capital provides the company not only with the resources to expand its footprint but also the stability to navigate the inherent risks of a rapidly evolving wellness landscape.